The zicam nasal swabs may cause you to lose your sense of smell:
http://health.msn.com/health-topics/...535>1=313036
In case you want the cliffs notes, this pretty much sums it up:
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According to Lee, both animal studies and historical medical literature indicate that zinc is actually toxic to the nerve receptors in the nose.
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Pretty shitty to hear since I used these things every time I got a cold. Haven't noticed any degradation of my olfactory system though...